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Saleem,Afia; Bukhari,Syed Majid; Zaidi,Asma; Farooq,Umar; Ali,Majid; Khan,Asma; Khan,Sidra; Shah,Kausar Hussain; Mahmood,Adeem; Khan,Farhan Ahmed. |
The 4-Hydroxycoumarin derivatives are known to show a broad spectrum of pharmacological applications. In this paper we are reporting the synthesis of a new series of 4-Hydroxycoumarin derivatives synthesized through Knovenegal condensation; they were characterized by using UV-Vis, FT-IR, NMR spectroscopies. The synthesized compounds were evaluated for antibacterial activity against Staphylococcus aureus and Salmonella typhimurium strains. The compounds (2), (3) and (8) showed favorable antibacterial activity with zone of inhibitions 26.5± 0.84, 26.0 ± 0.56 and 26.0 ± 0.26 against Staphylococcus aureus (Gram-positive) respectively. However, the compounds (5) and (9) were found more active with 19.5 ± 0.59 and 19.5 ± 0.32 zone of inhibitions against... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: 4-Hydroxycoumarin; Anti-urease; Carbonic anhydrase; Aldehydes; Antibacterial. |
Ano: 2020 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502020000100580 |
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Chopin, Christine; Kone, Matenin; Serot, Thierry. |
The aim of this study was to assess the modifications of fish myosin induced by interactions with four aldehydes: hexanal, 2-hexenal, 2,4-hexadienal, and 2,6-nonadienal. These compounds are generated during lipid oxidation and are known to have an impact on the functional properties of proteins. The interactions between protein and aldehydes were highlighted by measuring the content of aldehydes in the gaseous phase by the SPME-GC technique. Results show that the partition of aldehydes between the proteinaceous system and the gas phase decreases with time, except for hexanal. This decrease is proportional to the number of carbons and double bonds. The reaction between myosin and unsaturated aldehydes induces a decrease in the free sulfhydryl and amino... |
Tipo: Text |
Palavras-chave: SPME; Interactions; Aldehydes; Fish myosin. |
Ano: 2007 |
URL: http://archimer.ifremer.fr/doc/2007/publication-2676.pdf |
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